Betastasis

Massie et al. - The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis

Time series plot

Description

<p>Time series of the relative expression of a gene after exposure to 0.1% ethanol or 1nM R1881. Dark colored lines indicate averaged expression across replicates, relative to untreated LNCaP cells. The lightly shaded areas indicate the standard error of the mean.</p> <p>From the paper: Forty-eight total RNA samples were harvested from LNCaP cells grown for 72 h in steroid depleted medium (RPMI supplemented with 10% charcoal dextran-stripped FBS). These comprised 3 time zero samples; 10 vehicle (ethanol) control samples taken at 2, 4, 8, 12 and 24 h in duplicate; 36 androgen (R1881)-treated samples taken every 30 min for 4 h then every hour until 24 h following treatment (with replicates at 1, 2, 4, 8, 12, 16, 20 and 24 h).</p>